Description

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Dosage

Inside, regardless of the meal.

Schizophrenia: it is recommended to prescribe Abilifai at an initial dose of 10 or 15 mg 1 time a day. The maintenance dose is 15 mg / day. Clinical studies have shown the effectiveness of the drug in doses from 10 to 30 mg / day.

Manic episodes in bipolar disorder: the drug should be taken starting with a dose of 15 or 30 mg / day. Dose changes, if necessary, should be carried out at intervals of at least 24 hours. Clinical studies have demonstrated the effectiveness of the drug in doses of 15-30 mg / day for manic episodes when taken for 3-12 weeks. The safety of doses above 30 mg/day has not been evaluated in clinical studies.

When monitoring patients with type I bipolar disorder and manic or mixed episodes who had no symptoms while taking Abilifaya (15 or 30 mg / day at an initial dose of 30 mg / day) for 6 weeks, a favorable effect of such maintenance therapy was established. Patients should be periodically examined to determine whether maintenance therapy should be continued.

There is no need to change the dosage of the drug when prescribing the drug to patients with renal insufficiency, hepatic insufficiency (class A, B and C according to the Child-Pugh classification).

Although the experience of using the drug in patients over the age of 65 is limited, dose adjustment is not required for this category of patients.

Contraindications

Hypersensitivity to aripiprazole or any other component that is part of the drug.

age up to 18 years.

With caution:

patients with cardiovascular diseases (coronary heart disease or myocardial infarction, heart failure and conduction disorders);

patients with cerebrovascular diseases and conditions predisposing to hypotension (dehydration, hypovolemia and taking antihypertensive drugs), due to the possibility of developing orthostatic hypotension;

patients with seizures or suffering from diseases in which seizures are possible;

patients with an increased risk of hyperthermia, for example, with intense physical exertion, overheating, taking anticholinergic drugs, dehydration (due to the ability of neuroleptics to disrupt thermoregulation);

patients with an increased risk of aspiration pneumonia (due to the risk of impaired motor function of the esophagus and aspiration);

patients suffering from obesity and diabetes in the family.