Description

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Dosage regimen

Applied externally. The cream is applied in a thin layer on the previously cleaned surface of the condyloma and gently rubbed into the skin until completely absorbed. The cream should be applied only to the affected area, avoiding contact with internal surfaces.

Aldara cream is applied 3 times a week (for example, Monday, Wednesday and Friday or Tuesday, Thursday and Saturday) before going to bed, and is left on the skin for approximately 6-10 hours, during which time you should not take a shower or bath. A bandage should not be applied to the area of application of the cream. After this period, the cream should be washed off with water and mild soap.

Treatment should be continued until the disappearance of visible genital or perianal condylomas, but no more than 16 weeks.

Aldara cream is packed in disposable sachets containing the necessary amount of cream for application to the affected area, with an area of 20 cm2.

Do not apply the cream more than 1 time / day.

It is not allowed to use an excessive amount of cream.

Side effect

The frequency of side effects is defined as follows: very often (>1/10), often (<1/10, >1/100), infrequently (<1/100, >1/1000), rarely (<1/1000, >1/10 000), very rarely (<1/10 000).

Local skin reactions: very often – itching and pain at the site of application of the cream; often – infection, erythema, erosion, excoriation / peeling and swelling; infrequently – itching, dermatitis, folliculitis, erythematous rash, eczema, urticaria; rarely – induration, ulceration, scab formation and the appearance of bubbles, local hypopigmentation and hyperpigmentation.

From the central nervous system and peripheral nervous system: often – headache, dizziness; infrequently – insomnia, depression, irritability, paresthesia, migraine, drowsiness, ringing in the ears.

From the digestive system: often – nausea; infrequently – abdominal pain, diarrhea, vomiting, anorexia, pain in the anus, lesions of the rectum.

From the side of the reproductive system: infrequently – fungal and bacterial infection, herpes simplex, vaginitis, vulvitis, painful sexual intercourse, pain in the penis, vagina, atrophic vaginitis.

From the hematopoiesis system: very rarely – decreased hemoglobin, leukopenia, absolute neutropenia and thrombocytopenia.

From the musculoskeletal system: infrequently – lower back pain, arthralgia.

From the respiratory system: infrequently – pharyngitis, rhinitis.

From the body as a whole: often – infection, myalgia, fever, flu-like symptoms, fatigue; infrequently – excessive sweating, lymphadenopathy.

If local side effects occur, the cream should be removed by washing it off with soap and water. Treatment can be resumed after the skin reaction is stopped.

Contraindications to use

children under 18 years of age (due to lack of data); hypersensitivity to imihimod or any other components of the cream.

Use during pregnancy and lactation

Use during pregnancy is possible according to strict indications, if the intended benefit to the mother exceeds the potential risk to the fetus.

If it is necessary to use the drug during lactation, breastfeeding should be discontinued.