(27 customer reviews)

Allopurinol is an arthrifuge which inhibits xanthine oxidase and prevents formation of uric acid, from xanthine and hypoxanthine.

SKU: Allopurinol Category:
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Dosage regimen

The method of application and dosage regimen of a particular drug depend on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly observe the compliance of the used dosage form of a particular drug with the indications for use and the dosage regimen. They are set individually, under the control of the concentration of urates and uric acid in the blood and urine. Adults when ingested – 100-900 mg / day, depending on the severity of the disease. The frequency of intake is 2-4 times / day after meals. Children under the age of 15 years – 10-20 mg / kg / day or 100-400 mg / day. Maximum doses: with impaired renal function (including those caused by urate nephropathy) – 100 mg / day. An increase in the dose is possible in cases when, against the background of ongoing therapy, an increased concentration of urates in the blood and urine remains.

Side effect

From the cardiovascular system: in isolated cases – arterial hypertension, bradycardia. From the digestive system: dyspeptic phenomena are possible (including nausea, vomiting), diarrhea, transient increase in the activity of transaminases in the blood serum; rarely – hepatitis; in isolated cases – stomatitis, liver dysfunction (transient increase in the activity of transaminases and alkaline phosphatase), steatorrhea. From the central nervous system and peripheral nervous system: in isolated cases – weakness, fatigue, headache, dizziness, ataxia, drowsiness, depression, coma, paresis, paresthesia, convulsions, neuropathies, visual disturbances, cataracts, changes in the papilla of the optic nerve, taste disorders. From the hematopoiesis system: in some cases – thrombocytopenia, agranulocytosis and aplastic anemia, leukopenia (most likely in patients with impaired renal function). From the urinary system: rarely – interstitial nephritis; in isolated cases – edema, uremia, hematuria. From the endocrine system: in isolated cases – infertility, impotence, gynecomastia, diabetes mellitus. From the side of metabolism: in isolated cases, hyperlipidemia. Allergic reactions: skin rash, hyperemia, itching; in some cases – angioimmunoblastic lymphadenopathy, arthralgia, fever, eosinophilia, fever, Stevens-Johnson syndrome, Lyell syndrome. Dermatological reactions: in isolated cases – furunculosis, alopecia, hair discoloration.

Contraindications to use

Severe liver and /or kidney dysfunction, pregnancy, lactation, hypersensitivity to allopurinol.

27 reviews for Allopurinol

  1. Deborah Munoz

  2. Mary Melton

  3. Megan Kemp

  4. Gabriel Waters

  5. Catherine Swanson

  6. Aaron Lamb

  7. Roger Stone

  8. Isabella Dickson

  9. Alexis Diaz

  10. Eugene Oconnor

  11. Aaron Frost

  12. Barbara Wallace

  13. Michael Frost

  14. Christian Vo

  15. Elizabeth Luna

  16. Danielle Keith

  17. Carl Galvan

  18. Sarah Snow

  19. Jonathan Gomez

  20. Michelle Chen

  21. Patricia Baker

  22. Doris Beltran

  23. Ryan Underwood

  24. Donna Spencer

  25. Stephanie Mullins

  26. Jesse Magana

  27. Helen Orr

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