(27 customer reviews)

Anafranil works on the central nervous system and treats obsessive compulsive disorder, panic attacks, depression, and ongoing pain.

SKU: Anafranil Category:
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Adult treatment of depressive states of various etiologies occurring with various symptoms: endogenous, reactive, neurotic, organic, masked, involutional forms of depression; depression in patients with schizophrenia and psychopathies; depressive syndromes arising in old age due to chronic pain syndrome or chronic somatic diseases; depressive mood disorders of reactive, neurotic or psychopathic nature; obsessive-compulsive syndromes; chronic pain syndrome; phobias and panic attacks; cataplexy accompanying narcolepsy. Children and adolescents obsessive-compulsive syndromes; nocturnal enuresis (only in patients over the age of 5 years and subject to the exclusion of organic causes of the disease). Before starting Anafranil therapy for nocturnal enuresis in children and adolescents, the ratio of potential benefit and risk for the patient should be assessed. The possibility of alternative therapy should be considered. Currently, there is insufficient evidence of the efficacy and safety of clomipramine in children and adolescents in the treatment of depressive states of various etiologies, occurring with different symptoms, phobias and panic attacks, cataplexy, concomitant narcolepsy and chronic pain syndrome. Therefore, the use of Anafranil in children and adolescents (0-17 years old) is not recommended for these indications.

Use during pregnancy and lactation

The experience of using Anafranil during pregnancy is limited. Since there are isolated reports of a possible link between taking tricyclic antidepressants and fetal developmental disorders, the use of Anafranil during pregnancy should be avoided, except in cases where the expected effect of the mother’s treatment undoubtedly exceeds the potential risk to the fetus. In cases where tricyclic antidepressants were used during pregnancy until the onset of labor, newborns developed withdrawal syndrome during the first few hours or days, manifested by shortness of breath, drowsiness, colic, irritability, hypotension or hypertension, tremor, spastic phenomena or convulsions. In order to avoid the development of this syndrome, Anafranil should be gradually canceled, if possible, at least 7 weeks before the expected delivery. Since the active substance of the drug is excreted in breast milk, you should either stop breastfeeding, or gradually cancel Anafranil.


Hypersensitivity to clomipramine or any other ingredients of the drug, cross hypersensitivity to tricyclic antidepressants of the dibenzazepine group. Antiarrhythmic drugs, such as quinidine and propafenone, which potentiate the inhibition of CYP 2D6, should not be prescribed in combination with tricyclic antidepressants. Simultaneous use of MAO inhibitors, as well as a period of less than 14 days before and after their use. The combined use of selective MAO-A-reversible inhibitors, such as moclobemide, is also contraindicated. Recently suffered a myocardial infarction. Congenital syndrome of prolonged Q–T interval. Anafranil should not be prescribed to patients with: acute intoxication with CNS depressants (such as sleeping pills, analgesics or psychotropic drugs) or alcohol; acute urinary retention; acute delirium; untreated angle-closure glaucoma; prostatic hypertrophy with residual urinary retention; pylorostenosis; paralytic intestinal obstruction.

27 reviews for Anafranil

  1. Diana Roy

  2. Debra Stevenson

  3. Alice Peck

  4. Ethan Bartlett

  5. Amanda McGee

  6. Heather Black

  7. Betty Gibbs

  8. James Bowers

  9. Lauren Parra

  10. Ruth Espinosa

  11. Bruce Bell

  12. Samantha Hammond

  13. Natalie Norris

  14. Johnny Petersen

  15. Stephen Lyons

  16. Brittany Hahn

  17. Paul Fox

  18. Amy Holt

  19. Sharon Maxwell

  20. Pamela Everett

  21. Eugene Spencer

  22. Stephen Douglas

  23. Danielle Baxter

  24. Robert Shaw

  25. Peter Dennis

  26. Barbara Garza

  27. Jason Scott

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