Benemid

(21 customer reviews)

Benemid is used to reduce blood uric levels in the patietns with gout and gouty arthritis.

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Description

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Release form

The drug has the form of tablets placed in packages of 30 pieces.

Pharmacological action

Probenecid suppresses tubular reabsorption of uric acid, which increases uricosuria, thereby significantly reducing the level of uric acid in serum and mobilizing urate deposits in tissues. To avoid crystallization or even deposition of excess uric acid excreted by the kidneys, significant hydration at the beginning of treatment increases the solubility of uric acid in urine by neutralizing urine.

Pharmacokinetics

Absorption after oral administration of probenecid is rapid and complete. Probenecid binds to plasma proteins by 83-94% dose-dependent. It penetrates the blood-brain barrier. The substance undergoes extensive metabolism. About 77-88% is excreted through the kidneys, of which only 5-17% is unchanged. The rest is excreted as metabolites.

How to use Benemid?

The doctor prescribes the dosage, regimen and duration of therapy. According to the standard scheme, in the first 7 days of treatment, half a tablet of Benemide should be taken twice a day (preferably after the same period of time, for example, at 8:00 and at 20:00). Then, from the 8th to the 28th day of therapy, patients take 1 tablet of the drug twice a day. After a month of treatment, the patient undergoes condition monitoring, according to the results of which the doctor corrects therapy. Treatment can last a lifetime. The maximum daily dose is 4 tablets (2 g).

Contraindications and side effects of Benemid

In most cases, the drug is well tolerated. Sometimes patients have skin rashes, palpitations, shortness of breath. Contraindications are hypersensitivity to the components of the drug, pregnancy, urolithiasis. During chemotherapy, Benemide should be discontinued.

21 reviews for Benemid

  1. Scott Reese

  2. Roger Montoya

  3. Hannah Velazquez

  4. Ann Simmons

  5. Christina Finley

  6. Donna Blankenship

  7. Theresa Nguyen

  8. Brian Vang

  9. Nicholas Salgado

  10. Katherine Wiggins

  11. Emily Barajas

  12. Bryan Morton

  13. Lawrence Roach

  14. Donna Collier

  15. Aaron Branch

  16. Gloria Hubbard

  17. Janice Estrada

  18. Jesse Lewis

  19. Walter Dodson

  20. Sharon Ballard

  21. Emma Jarvis

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