Description
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Indications
Erectile dysfunction (inability to achieve and maintain an erection necessary for sexual intercourse). In order for Levitra® to be effective, sexual stimulation is required.
Contraindications
– Hypersensitivity to vardenafil or to any of the excipients; – simultaneous use with nitrates or drugs that are donors of nitric oxide; – simultaneous use with riociguate, a stimulant of soluble guanylate cyclase; – simultaneous use with powerful CYP3A4 inhibitors, such as ketoconazole and itraconazole (in dosage forms for oral administration) in men over 75 years of age; indinavir, ritonavir and their combinations; drugs containing cobicistat; – severe chronic heart failure (functional class III-IV according to NYHA classification); – in patients with a history of unilateral vision loss due to non-arteritic anterior ischemic optic neuropathy, regardless of the connection with previous administration of PDE-5 inhibitors.
Dosage regimen
The method of application and dosage regimen of a particular drug depend on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly observe the compliance of the used dosage form of a particular drug with the indications for use and the dosage regimen. At the beginning of treatment, the recommended dose is 10 mg. Taken orally, if necessary, approximately 25-60 minutes before sexual contact. Along with this, vardenafil can also be taken at any time in the period from 4-5 hours to 25 minutes before sexual activity. The maximum recommended frequency of reception is 1 time / day. Vardenafil can be taken regardless of the meal. To achieve the effectiveness of treatment, a sufficient level of sexual stimulation is necessary. Depending on the effectiveness and tolerability of treatment, the dose can be increased to 20 mg or reduced to 5 mg / day. The maximum recommended dose is 20 mg 1 time / day. In elderly patients, changes in the dosage regimen are not required. In patients with moderate hepatic impairment, there is a decrease in the clearance of vardenafil, so the initial dose is 5 mg / day. In the future, depending on the effectiveness and tolerability of the drug, the dose can be increased to 10 mg and then to 20 mg.
Side effect
From the nervous system: headache, dizziness are possible; rarely – increased muscle tone. From the cardiovascular system: possible redness of the face; rarely – an increase in blood pressure, a decrease in blood pressure. From the digestive system: possible – dyspepsia, nausea. From the respiratory system: nasal congestion is possible. Dermatological reactions: rarely – photosensitivity. From the side of the reproductive system: rarely – priapism.
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