Calan Sr

(34 customer reviews)

Calan Sr is a calcium channel blocker, it is effective in treatment of hypertension, stenocardia, etc.

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Description

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Overdose

Symptoms: large doses (taking up to 6 g of the drug) can cause deep depression of consciousness, arterial hypotension, sinus bradycardia, turning into AV blockade, sometimes asystole. Treatment: in case of arterial hypotension and / or complete AV blockade – intravenous injection of fluid, dopamine (dopamine), calcium gluconate, isoproterenol or norepinephrine. Treatment is symptomatic and depends on the clinical picture of overdose. Hemodialysis is not effective. Symptoms: pronounced bradycardia, AV blockade, decreased blood pressure, heart failure, sinoatrial blockade. Treatment: with early detection, gastric lavage is performed if less than 12 hours have passed since taking the drug, as well as at a later date with reduced gastrointestinal motility (absence of intestinal noises during auscultation). Symptomatic therapy: for rhythm and conduction disorders – intravenous isoprenaline, epinephrine, atropine, calcium gluconate 10% solution 10-20 ml, artificial pacemaker, intravenous infusion of plasma-substituting solutions. Hemodialysis is not effective. Symptoms of poisoning as a result of an overdose of the drug Isoptin depend on the amount of the drug taken, the time of detoxification measures and on the contractility of the myocardium (depending on age). Fatal cases have been reported as a result of overdose. The following symptoms prevail: a drop in blood pressure (in some cases to levels that cannot be measured); shock, loss of consciousness; AV blockade of I and II degrees, often with Wenckebach periods with or without a slipping rhythm; complete AV blockade with complete AV dissociation, slipping rhythm, cardiac arrest; sinus bradycardia, sinus node arrest. Treatment. Therapeutic measures should be carried out depending on the duration and method of taking the drug Isoptin and on the nature and severity of poisoning symptoms. In case of overdose with a large number of coated tablets of prolonged action (i.e., with the drug Isoptin CP 240), it should be borne in mind that the active substance is released and absorbed in the intestine within 48 hours after ingestion of the drug. Depending on the time of ingestion of the drug, individual conglomerates of the remnants of swollen tablets acting as active depots are likely to be located throughout the gastrointestinal tract. General events. If there is no motility of the stomach and intestines (signs of peristalsis during auscultation), it is advisable to perform gastric lavage even 12 hours after ingestion of the drug. If there is a suspicion of an overdose of the drug Isoptin CP 240, then appropriate measures aimed at removing the drug are indicated, for example, vomiting should be induced, the stomach and intestines should be washed in combination with an endoscopic examination, laxatives, emetics should be taken. The usual emergency resuscitation measures include closed heart massage, artificial respiration and electrical stimulation of the heart. Special events. Exclusion of effects associated with depression of heart function, arterial hypotension and bradycardia. Calcium is a specific antidote: 10-30 ml of 10% calcium gluconate solution is administered as an intravenous injection (2.25-4.5 mmol), if necessary, re-administered or as a slow drip infusion (for example, 5 mmol / h). The following activities may be required. In case of AV block of II or III degree, sinus bradycardia, cardiac arrest: atropine, isoprenaline, orciprenaline or cardiac stimulation. In case of arterial hypotension: dopamine, dobutamine, norepinephrine. In case of persistent signs of myocardial insufficiency: dopamine, dobutamine, additional calcium injections if necessary.

34 reviews for Calan Sr

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  2. Diane Adams –

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