Casodex

(40 customer reviews)

Casodex treats metastatic prostate cancer and hirsutism in men.

SKU: Casodex Categories: ,
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Description

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Contraindications

Hypersensitivity (hypersensitivity reactions have been reported, including angioedema and urticaria).

Use during pregnancy and lactation

Bicalutamide is contraindicated for use in pregnant women, because it can harm the fetus. Bicalutamide is not indicated for use in women. There is no data on the use of bicalutamide in pregnant women. In animal reproduction studies, oral administration of bicalutamide to pregnant rats during organogenesis caused abnormal development of reproductive organs in male fetuses at an exposure approximately 0.7-2 times higher than human exposure at the recommended dose. There is no information indicating the presence of bicalutamide in breast milk in women, as well as its effect on the infant or milk production. Bicalutamide was found in the milk of rats.

Special instructions

The drug is metabolized in the liver. Given the possibility of slowing the excretion of bicalutamide and accumulation of bicalutamide in patients with severe hepatic impairment, it is advisable to periodically evaluate liver function. Most changes in liver function occur during the first 6 months of Casodex treatment. Casodex® should be used with caution in patients with moderate to severe hepatic impairment. Severe liver dysfunction with the use of Casodex rarely develops (fatal cases have been reported). In case of development of pronounced changes in liver function, Casodex should be discontinued. In patients with disease progression against the background of increased levels of prostate-specific antigen (PSA), it is necessary to consider discontinuing treatment with Casodex. Given the possibility of inhibition of cytochrome P450 (CYP3A4) activity by Casodex, caution should be exercised when concomitantly prescribing Casodex with drugs primarily metabolized with the participation of CYP3A4. In patients taking GnRH agonists, there was a decrease in glucose tolerance. This effect can lead to the development of diabetes mellitus or a decrease in glucose tolerance in patients with diabetes mellitus. Therefore, in patients taking Casodex® and GnRH agonists, it is necessary to monitor blood glucose concentrations.

40 reviews for Casodex

  1. Eugene Klein

  2. Deborah Abbott

  3. Helen Bruce

  4. Christina McCoy

  5. Alice Wheeler

  6. Katherine Richards

  7. Melissa Bentley

  8. Michelle Pratt

  9. Sharon Becker

  10. Austin Noble

  11. Susan Baker

  12. Cheryl Scott

  13. Stephanie Wyatt

  14. Barbara Lewis

  15. Dennis Hodges

  16. Steven Kirk

  17. Russell Parker

  18. Aaron Miller

  19. Julie Conley

  20. Marie Cantrell

  21. Keith Fernandez

  22. Robert Webster

  23. Kayla Saunders

  24. Jerry Delarosa

  25. Dylan Harris

  26. Jennifer Neal

  27. Mary Velazquez

  28. Stephanie Gordon

  29. Carl Decker

  30. Eric Keller

  31. Ruth Fitzpatrick

  32. Frank Young

  33. Doris Robbins

  34. Jason Barr

  35. Jessica Clark

  36. Michael Andersen

  37. Frank Davidson

  38. Robert Nguyen

  39. Janice Vincent

  40. Nancy Maynard

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