Description

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Dosage regimen

Inside, 30-60 minutes before meals, with water.

The average dose for adults and children over 10 years of age is 250-500 mg every 6 hours. The daily dose of the drug should be at least 1-2 g, if necessary, it can be increased to 4 g. The duration of the course of treatment is 7-14 days. For infections caused by beta-hemolytic streptococcus group A, the minimum duration of treatment is 10 days.

In adult patients with impaired renal function, the daily dose is reduced taking into account the CC value: with a CC of 5-20 ml / min, the maximum daily dose is 1.5 g / day; with a CC of less than 5 ml / min, 0.5 g / day. The daily dose is divided into 4 doses.

For children under the age of 10, the drug is recommended to be prescribed in the form of a suspension for oral administration. With a body weight of less than 40 kg, the average daily dose is 25-100 mg / kg of body weight; the frequency of administration is 4 times / day. With otitis media, the dose is 75 mg / kg / day, the frequency of administration is 4 times / day. With streptococcal pharyngitis, skin and soft tissue infections, the frequency of administration is 2 times / day. In severe infections, the daily dose can be increased to 100 mg / kg of body weight, and the frequency of administration – up to 6 times / day.

Preparation of suspension: add water to the bottle until risked and shake well. The prepared suspension is stable at room temperature for 14 days. Before each use, the suspension must be shaken. 5 ml of the finished suspension contains 250 mg of cephalexin.

Side effect

Allergic reactions: rash, urticaria, Quincke’s edema, erythema, rarely – eosinophilia, toxic epidermal necrolysis, Stevens-Johnson syndrome, anaphylactic shock.

From the digestive system: abdominal pain, dry mouth, anorexia, nausea, vomiting, diarrhea, toxic hepatitis, cholestatic jaundice, increased activity of hepatic transaminases and alkaline phosphatase, intestinal candidiasis, oral cavity, pseudomembranous enterocolitis.

From the nervous system: dizziness, weakness, headache, agitation, hallucinations, convulsions.

From the genitourinary system: interstitial nephritis, itching of the genitals and anus, vaginitis, vaginal discharge, candidiasis of the genitals.

From the hematopoietic organs: leukopenia, neutropenia, thrombocytopenia.

From the musculoskeletal system: arthralgia, arthritis.

Laboratory indicators: increased prothrombin time.

Contraindications to use

children under 3 years of age (for the dosage form – capsules); hypersensitivity (including to other beta-lactam antibiotics).

With caution – renal insufficiency, pseudomembranous colitis (in anamnesis), pregnancy, lactation, infancy (up to 6 months – for suspension).

Use during pregnancy and lactation

The use of the drug during pregnancy and lactation is possible only if the intended benefit to the mother exceeds the potential risk to the fetus.

If it is necessary to prescribe the drug during lactation, breastfeeding should be discontinued.