Description
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The use of Crestor
Before starting treatment, the patient should be prescribed a standard lipid-lowering diet, which must be followed during treatment. The dose is selected individually depending on the purpose of therapy and the patient’s response to treatment, guided by the recommendations of current generally accepted guidelines. Crestor can be taken at any time of the day, regardless of the meal. Treatment for hypercholesterolemia. The recommended initial dose is 5 or 10 mg orally once a day for both patients who have not previously used statins and transferred to the drug after taking another HMG-CoA reductase inhibitor. When choosing the initial dose, it is necessary to take into account the levels of cholesterol in each individual patient and the risk of cardiovascular disorders in the future, as well as the likelihood of adverse reactions. If necessary, the dose can be increased to the next level after 4 weeks (see Pharmacodynamics). Taking into account the fact that against the background of the use of the drug at a dose of 40 mg, adverse reactions occur more often than at lower doses (see SIDE EFFECTS), it is necessary to finally titrate the dose to 40 mg only in patients with severe hypercholesterolemia and a high risk of cardiovascular disorders (in particular, in patients with familial hypercholesterolemia), who failed to achieve the goal of treatment with a dose of 20 mg and who will be under regular supervision.
Contraindications
Hypersensitivity;liver diseases in the active phase, including a persistent increase in the serum activity of transaminases and any increase in the activity of transaminases in serum (more than 3 times compared with the IOP);severe renal dysfunction (creatinine Cl less than 30 ml / min);myopathy;simultaneous administration of cyclosporine; in women: pregnancy, lactation, lack of adequate methods of contraception;patients predisposed to the development of myotoxic complications;lactose intolerance, deficiency lactase or glucose-galactose malabsorption (the drug contains lactose).
Nicholas Allen –
Richard Booker –
Cynthia Williamson –
Jason Palacios –
Rachel Silva –
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Walter Romero –
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