(22 customer reviews)

Cytoxan is used for treatment of cancer with cytotoxic effect.

SKU: Cytoxan Category:
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Pharmacological action

Antitumor agent of alkylating action, also has an immunosuppressive effect. It is an inactive transport form that decays under the action of phosphatases with the formation of an active component directly in tumor cells, “attacks” the nucleophilic centers of protein molecules, disrupts the synthesis of DNA and RNA, blocks mitotic division.

Side effects

Nausea, vomiting, toxic hepatitis; alopecia; abacterial hemorrhagic cystitis; leukopenia, thrombocytopenia; myalgia, ossalgia, headache.
Special instructions
During treatment, it is necessary to monitor the picture of peripheral blood: during the main course – 2 times a week, with maintenance therapy – 1 time a week. With a decrease in leukocytes to 2.5 thousand / ml and platelets – up to 100 thousand / ml, treatment should be discontinued. When used in higher doses for the prevention of hemorrhagic cystitis, it is advisable to prescribe uromitexan (mesna). It is necessary to consume more fluids during treatment. When using cyclophosphamide for the treatment of non-tumor diseases, extreme caution is recommended due to the possible carcinogenic effect of the drug with prolonged use.


The drug may enhance the effect of hypoglycemic drugs. Simultaneous administration of allopurinol may lead to more pronounced myelodepression. Increases cardiotoxicity of adriamycin and rubromycin. The effect of cyclophosphamide is enhanced by chlorpromazine, tricyclic antidepressants, barbiturates, theophylline, hingamine, thyroid hormones, reduce (including toxic effect) – GCS, chloramphenicol.

22 reviews for Cytoxan

  1. Jacob Lynch

  2. Larry Ho

  3. Diana Cantu

  4. Mark Edwards

  5. Melissa McCormick

  6. Scott McBride

  7. Richard Cortes

  8. Ruth Skinner

  9. Julia Douglas

  10. Julie Wyatt

  11. Ralph Singh

  12. Diane Wright

  13. Dorothy Wilkinson

  14. Jeffrey Frye

  15. Logan Huang

  16. Steven Spence

  17. Diana Colon

  18. Shirley Michael

  19. Nancy Nichols

  20. Maria Shelton

  21. Charles Ray

  22. Patricia Ho

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