Description
Looking for a drugstore where you can buy Differin online? You can go to link and go to the pharmacy with the best prices. Anonymous delivery, quality drugs, absolutely confidentiality. Go to an online pharmacy and choose the appropriate Differin dosage, and then the required amount of pills. The purchase process will be as secure and safe as possible. You can also order Differin with fast delivery at the pharmacy, the drug will be delivered tomorrow. The getting is made without a prescription because we trust you and understand that you already know which medicine you need.
Pharmacodynamics
Adapalene is a retinoid metabolite that acts on the pathological mechanism of development Acne vulgaris, is a strong modulator of cellular differentiation and keratinization and has comedonolytic and anti-inflammatory activity. The mechanism of action of adapalene is based on interaction with specific gamma receptors of epidermal skin cells. As a result of the action of adapalene, there is a decrease in the “cohesion” of epithelial cells at the mouth of the sebaceous hair follicle and a decrease in the formation of microcomedones. Adapalene has an anti-inflammatory effect in vivo and in vitro, acting on inflammatory factors by inhibiting the migration of leukocytes in the focus of inflammation, inhibits the chemotactic and chemokinetic responses of human polymorphonuclear leukocytes and suppresses the metabolism of arachidonic acid to inflammatory mediators, AP-1 factors and the expression of Toll-like receptors 2.
Special instructions
Avoid getting gel or cream in the eyes, on the lips and on the mucous membranes. In case of accidental contact of the drug on the mucous membranes of the eyes, mouth or nose, rinse them thoroughly with warm water. Avoid direct sunlight, as slight skin irritation may occur. Treatment can be continued if the sun exposure is minimized (the use of sunglasses and hats). Simultaneous use of cosmetics with a drying or irritating effect on the skin (for example, perfumes or alcohol-containing products) is not recommended. Adapalene applied to the skin in the evening can be combined with acne medications used in the morning.
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