(37 customer reviews)

Diflucan is anti-fungal antibiotic used against candidiasis of different organs including genital area.

SKU: Diflucan Categories: ,
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Side effect

Frequency evaluation criteria: very common (≥10%); common (≥1% and <10%); infrequent (≥0.1% and <1%); rare (≥0.01% and <0.1%); very rare (<0.01%); frequency unknown (impossible to determine based on available data).

The tolerability of the drug is usually very good.

In clinical and post-marketing (*) studies of the drug Diflucan®, the adverse reactions presented below were noted.

From the nervous system: often – headache; infrequently – dizziness *, convulsions*, taste changes*, paresthesia, insomnia, drowsiness; rarely – tremor.

From the digestive system: often – abdominal pain, diarrhea, nausea, vomiting*; infrequently – flatulence, dyspepsia*, dryness of the oral mucosa, constipation.

From the side of the hepatobiliary system: often – increased serum activity of aminotransferases (ALT and AST), alkaline phosphatase; infrequently – cholestasis, jaundice*, increased bilirubin concentration; rarely – hepatotoxicity, in some cases fatal, liver dysfunction*, hepatitis*, hepatocellular necrosis*, hepatocellular damage.

From the skin: often – rash; infrequently – skin itching, urticaria, increased sweating, drug rash (including persistent drug rash); rarely – exfoliative skin lesions*, including Stevens-Johnson syndrome and toxic epidermal necrolysis, acute generalized exanthematous pustulosis, facial edema, alopecia*; frequency unknown – drug rash with eosinophilia and systemic symptoms (DRESS syndrome).

From the hematopoiesis system*: rarely – leukopenia, including neutropenia and agranulocytosis, thrombocytopenia, anemia.

On the part of the immune system*: anaphylaxis (including angioedema).

From the cardiovascular system*: rarely – an increase in the QT interval on the ECG, ventricular tachysystolic arrhythmia of the “pirouette” type (torsade de pointes).

From the side of metabolism*: rarely – an increase in the concentration of cholesterol and triglycerides in blood plasma, hypokalemia.

From the musculoskeletal system: infrequently – myalgia.

Other: infrequently – weakness, asthenia, fatigue, fever, vertigo.

In some patients, especially with serious diseases such as AIDS or cancer, changes in blood parameters, kidney and liver function were observed during treatment with Diflucan® and similar drugs, but the clinical significance of these changes and their relationship with treatment have not been established.

Contraindications to use

simultaneous use of terfenadine during repeated administration of fluconazole at a dose of 400 mg / day or more; simultaneous use with drugs that increase the QT interval and are metabolized by the CYP3A4 isoenzyme, such as cisapride, astemizole, erythromycin, pimozide and quinidine; lactase deficiency, galactose intolerance, glucose-galactose malabsorption; children under 3 years of age (for this dosage form); hypersensitivity to fluconazole, other components of the drug or azole substances with a structure similar to fluconazole.

With caution: liver failure; renal failure; the appearance of a rash against the background of the use of fluconazole in patients with superficial fungal infection and invasive / systemic fungal infections; simultaneous use of terfenadine and fluconazole at a dose of less than 400 mg / day; potentially proarrhythmic conditions in patients with multiple risk factors (organic heart disease, electrolyte imbalance and concomitant therapy contributing to the development of such disorders).

37 reviews for Diflucan

  1. Samantha Kirk

  2. Carol Little

  3. Jose Archer

  4. Christine Mathis

  5. Kimberly Tanner

  6. Isabella Glass

  7. Kathryn Lawrence

  8. Benjamin Felix

  9. Karen Glover

  10. Randy Wilcox

  11. Susan Turner

  12. Martha Ford

  13. Patrick Colon

  14. Arthur Lewis

  15. Maria Fowler

  16. Teresa Ellis

  17. Jessica Reyes

  18. Carl Campbell

  19. Theresa Baxter

  20. Shirley Orozco

  21. Gregory Camacho

  22. Deborah Keith

  23. Beverly Walter

  24. Gabriel Jones

  25. Terry Ayers

  26. Heather Moon

  27. Eugene Rivers

  28. Jack Todd

  29. Betty Rosas

  30. Theresa Huerta

  31. Jason Coffey

  32. Billy Esparza

  33. Laura Villa

  34. Linda Xiong

  35. Larry George

  36. Jose Hogan

  37. Nancy Hester

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