Epivir Hbv

(47 customer reviews)

Epivir Hbv is an antiviral medication used to fight infection with the human immunodeficiency virus (HIV), the deadly cause of AIDS.

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Description

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Dosage regimen

The method of application and dosage regimen of a particular drug depend on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly observe the compliance of the used dosage form of a particular drug with the indications for use and the dosage regimen.

The dose and treatment regimen are set depending on the indications.

Side effect

From the digestive system: pain and discomfort in the epigastric region, nausea, vomiting, diarrhea, decreased appetite, increased activity of hepatic transaminases. Autoimmune hepatitis may develop.

From the Central nervous System: increased fatigue, headache.

From the respiratory system: respiratory tract infections.

Other: general malaise.

Contraindications to use

Hypersensitivity to lamivudine.

Use during pregnancy and lactation

Despite the absence of direct indications of teratogenic effects and changes in reproductive function, lamivudine should be used during pregnancy only after a thorough assessment of the expected benefits and potential risk of side effects.

If it is necessary to use lamivudine during lactation, breastfeeding should be discontinued.

Use in cases of liver dysfunction

Correction of the dosage regimen in patients with impaired liver function is not required. However, it should be used with caution in patients with severe cirrhosis of the liver caused by the hepatitis B virus, given the risk of exacerbation of the disease after discontinuation of lamivudine.

Use in cases of impaired renal function

It is used with caution in cases of impaired renal function. With a CC of less than 50 ml / min, dose adjustment is necessary.

Use in children

There is no experience of using lamivudine in children younger than 3 months. In children with impaired renal function, it is recommended to adjust the dosage regimen in the same proportions as in adults.

Special instructions

It is used with caution in cases of impaired renal function. With a CC of less than 50 ml / min, dose adjustment is necessary.

Considering that lamivudine is excreted almost exclusively by the kidneys, correction of the dosage regimen in patients with impaired liver function is not required. However, it should be used with caution in patients with severe cirrhosis of the liver caused by the hepatitis B virus, given the risk of exacerbation of the disease after discontinuation of lamivudine.

Lamivudine is not used in combination with zidovudine for neutropenia (neutrophil count less than 750 / ml) or anemia (hemoglobin less than 7.5 g / dl or 4.65 mmol / l).

If abdominal pain, nausea, vomiting or an increase in the level of pancreatic enzymes in the blood plasma, lamivudine should be discontinued and its use should not be resumed until the diagnosis of pancreatitis is excluded.

The use of lamivudine does not prevent the possibility of infection through sexual contact or through blood.

During the treatment period, the possibility of developing a secondary infection should be borne in mind.

Use in pediatrics

There is no experience of using lamivudine in children under the age of 3 months. In children with impaired renal function, it is recommended to adjust the dosage regimen in the same proportions as in adults.

47 reviews for Epivir Hbv

  1. Mary Yoder –

  2. Raymond Shelton –

  3. Nicole McLaughlin –

  4. Kevin Cano –

  5. Julia Villegas –

  6. Ruth Norris –

  7. Kevin Holt –

  8. Alexis Zimmerman –

  9. Megan Cook –

  10. Michelle Yu –

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