Epivir

(49 customer reviews)

Epivir is an antiviral medication used to fight infection with the human immunodeficiency virus (HIV), the deadly cause of AIDS.

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Description

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Use during pregnancy and lactation

Pregnancy

There is currently insufficient data on the safety of lamivudine during pregnancy. Lamivudine should be used during pregnancy only if the expected benefit to the mother exceeds the potential risk to the fetus. Although the results of animal experiments cannot always be extrapolated to humans, data from studies on rabbits indicate a possible risk of spontaneous abortion in the early stages of pregnancy.

In newborns and children under the age of 1 year, whose mothers took drugs from the group of nucleoside reverse transcriptase inhibitors during pregnancy and childbirth, cases of a slight transient increase in serum lactic acid concentration, obviously caused by mitochondrial dysfunction, have been described. The clinical significance of a temporary increase in the concentration of lactic acid in serum has not been established. In addition, very rare cases of developmental delay, convulsive syndrome and other neurological disorders have been reported. However, the relationship of these complications with the use of nucleoside reverse transcriptase inhibitors during pregnancy and their effect on postnatal development has not been proven. Therefore, HIV-infected women during pregnancy are recommended to take antiretroviral drugs to prevent vertical transmission of HIV.

Lactation

According to experts, all HIV-infected women should, if possible, refuse to breastfeed in order to avoid transmission of the virus to the child through breast milk. After oral administration, lamivudine is excreted in breast milk; at the same time, its concentration in breast milk practically does not differ from its concentration in serum (1-8 mcg / ml). Women taking lamivudine are not recommended to breastfeed.

Contraindications

Hypersensitivity to lamivudine or any other component of the drug Epivir. The age is younger than 3 months due to the fact that data on the use of the drug in this age group are limited.

With caution

It should be used with caution in patients with renal insufficiency; pancreatitis (including a history); peripheral neuropathy; during pregnancy and lactation.

49 reviews for Epivir

  1. Wayne Ho

  2. Logan Salazar

  3. Katherine Rosario

  4. Logan Carpenter

  5. Charlotte Michael

  6. Elizabeth Carson

  7. Kevin McGee

  8. Ann Pratt

  9. Bobby Barnett

  10. Jesse Nicholson

  11. Christine Pitts

  12. Peter Harrison

  13. Samantha Rice

  14. Julie Cunningham

  15. Jason Sullivan

  16. Hannah Pruitt

  17. Harold Frost

  18. Megan Crawford

  19. Cynthia Christensen

  20. Natalie Adkins

  21. William Neal

  22. Roger Sheppard

  23. Jose Cervantes

  24. Paul Aguirre

  25. Jacqueline Barry

  26. Brittany Conrad

  27. Barbara White

  28. Kenneth Pena

  29. Matthew Wolf

  30. Bryan Horton

  31. Gabriel Caldwell

  32. Brittany Doyle

  33. Emma Rich

  34. Sharon Duke

  35. Eugene Foster

  36. Joshua Vaughan

  37. Ralph Duke

  38. Rose Mahoney

  39. Joe Strickland

  40. Frank Mills

  41. Karen Valdez

  42. Walter Li

  43. Jessica Ayala

  44. Susan Dyer

  45. Rebecca Zimmerman

  46. Albert Colon

  47. Charlotte Savage

  48. Ann Castaneda

  49. Johnny Meza

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