Glucotrol Xl

(34 customer reviews)

Glucotrol Xl is sulfonylurea class of drugs, a drug used to treat type 2 of diabetes.

SKU: Glucotrol Xl Category:
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Description

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Indications

Insulin-dependent diabetes mellitus (with excess or normal body weight).

Contraindications

Hypersensitivity, insulin-dependent diabetes mellitus (juvenile diabetes, diabetes accompanied by ketoacidosis or precoma); severe renal or hepatic insufficiency; digestive tract stenosis; childhood.

Use during pregnancy and lactation

Contraindicated during pregnancy. It should be prescribed with caution to nursing women (hypoglycemia in newborns is possible).

Side effects

Hypoglycemia; nausea, diarrhea, discomfort in the epigastric region; cholestatic jaundice, toxic hepatitis; leukopenia, agranulocytosis, thrombocytopenia, hemolytic or aplastic.

Pharmacokinetics

It is absorbed quite fully. 2-3 hours after administration, it is determined in plasma at a significant concentration, which, gradually increasing, reaches a maximum after 6-12 hours. Taking 1 time a day maintains an effective level for 24 hours. Bioavailability — 90%. In the blood, it binds to proteins by 99%. Stable plasma concentrations are achieved on the 5th day of use (in patients over 65 years of age — 1-2 days later). The pharmacokinetics of glipizide is linear in the dose range of 5-60 mg. It is eliminated by biotransformation in the liver, only less than 10% of the administered dose is excreted unchanged in urine and feces; biotransformation products are also excreted in urine (80%) and feces (10%).

Overdose

The effect is enhanced by miconazole, phenylbutazone, alcohol, beta—blockers, ACE inhibitors (captopril, enalapril), acetylsalicylic acid (in large doses), sulfonamides, reduced by danazole, chlorpromazine (100 mg / day), glucocorticosteroids and tetracosactide (including topical application), progestogens, ritodrin, salbutamol, terbutalin (parenterally).

34 reviews for Glucotrol Xl

  1. Joshua Good

  2. Kelly Rasmussen

  3. Mark Buck

  4. Henry Griffin

  5. Jason Daniels

  6. Shirley Saunders

  7. Marie Yates

  8. Matthew Mullins

  9. Carl Turner

  10. Brittany Barton

  11. Sophia Collier

  12. Laura Tanner

  13. Victoria Wyatt

  14. Roy Villarreal

  15. Julie Felix

  16. Logan Hodges

  17. Johnny Phelps

  18. Natalie Simpson

  19. Donna Sellers

  20. Charlotte Guzman

  21. Zachary Daniel

  22. Isabella Powers

  23. Patrick Roach

  24. Donna Allen

  25. Elizabeth Hopkins

  26. Louis Petersen

  27. Frank Ventura

  28. Brittany Truong

  29. Mary Grant

  30. Ethan Valencia

  31. Eric Heath

  32. Stephanie Avila

  33. Alexander Schroeder

  34. Roger Obrien

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