(30 customer reviews)

Imodium is an antidiarrheal drug which slows the rhythm of digestion and absorption of fluid in the small intestines.

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Special instructions

The treatment of diarrhea is symptomatic. If it is possible to determine the etiology of the disease (or it is indicated that this should be done), then, if possible, specific treatment should be carried out. In patients with diarrhea, especially in children, weakened patients and the elderly, dehydration and electrolyte imbalance may occur. In such cases, the most important measure is to carry out substitution therapy to replenish the supply of fluid and electrolytes. The use of the drug does not replace the introduction of an appropriate amount of fluid and electrolytes. Since persistent diarrhea may indicate a more serious condition, the drug should not be used for a long time until the cause of diarrhea is investigated. In acute diarrhea, when there is no clinical improvement within 48 hours, the use of loperamide hydrochloride should be discontinued and consult a doctor. Patients with acquired immunodeficiency syndrome who take Imodium for diarrhea should immediately stop treatment when the first signs of bloating appear. There are separate reports of cases of intestinal obstruction with an increased risk of toxic megocolon in the treatment of loperamide hydrochloride in patients with AIDS, infectious colitis of both viral and bacterial origin. Although there are no pharmacokinetic data for patients with impaired liver function, Imodium should be used with caution in such patients due to a slowdown in the metabolism of the first pass. Loperamide hydrochloride should be prescribed with caution to patients with impaired liver function, since it can lead to a relative overdose, which can cause toxic damage to the central nervous system. Medications that lengthen the passage time may lead to the risk of developing toxic megacolon in patients of this group. Considering that loperamide is well metabolized, as well as the fact that it and its metabolites are excreted in the feces, there is usually no need to adjust the dose of loperamide in patients with impaired renal function. Since the drug contains lactose, it should not be used in patients with rare hereditary forms of galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption syndrome. If the drug is taken to control episodes of diarrhea caused by IBS, which was previously diagnosed by a doctor, and clinical improvement is not observed within 48 hours, it is necessary to stop using loperamide hydrochloride and consult a doctor. You should also consult a doctor if the nature of the symptoms has changed or recurring episodes of diarrhea last more than 2 weeks. For the treatment of acute episodes of diarrhea caused by IBS, Imodium should be taken only if the doctor has previously diagnosed this disease. In the following cases, the drug is not recommended to be used without prior consultation with a doctor, even if it is known that the patient has IBS: the patient is over 40 years old and some time has passed since the last attack of IBS; the patient is over 40 years old and this time the symptoms of IBS are different; recent bleeding from the intestine; severe constipation; nausea or vomiting; loss of appetite or weight loss; difficult or painful urination; fever; recent trip abroad. In case of new symptoms, worsening of symptoms, or if symptoms have not improved within 2 weeks, it is necessary to consult a doctor. The period of pregnancy and lactation. It is not recommended to take this drug during pregnancy. In this regard, pregnant women and women who are breastfeeding should be advised to consult a doctor to receive appropriate treatment. Children. The drug is used in children over the age of 12 years for symptomatic treatment of acute diarrhea. 


If the dosage is exceeded (also in the case of a relative overdose with impaired liver function), there may be: urinary retention, intestinal obstruction, signs of central nervous system depression (stupor, impaired coordination, miosis, muscle hypertonia, etc.). Children have a greater sensitivity to the drug than adults. Therapy: antidote – naloxone (with its repeated administration, since the duration of action of Loperamide is longer than naloxone (1-3 hours)), simultaneous monitoring of the human condition (at least 48 hours).

30 reviews for Imodium

  1. Justin Griffith

  2. Theresa Camacho

  3. Timothy Arellano

  4. Juan Burton

  5. Theresa Duarte

  6. Barbara Whitney

  7. Deborah Mack

  8. Zachary Yang

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  10. Mary Francis

  11. James Evans

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  13. Donald Pace

  14. Deborah Lynn

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