Lopid

(50 customer reviews)

Lopid is used to lower triglyceride levels in patients with pancreatitis and reduce the risk of developing coronary heart disease.

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Description

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Lopid is a hypolipidemic agent, a derivative of fibroic acid. The mechanism of action of the drug is based on the activation of lipoprotein lipase, as well as the ability to increase the catabolism of triglycerides (TG) into very low density lipoproteins (VLDL) and accelerate the transition of cholesterol from atherogenic VLDL to anti-atherogenic high-density lipoproteins (HDL), while reducing the production of VLDL. Accelerates the circulation and removal of cholesterol from the liver, promotes the excretion of the latter with bile. Reduces the incorporation of long-chain fatty acids into newly synthesized triglycerides. In patients with mixed-type hyperlipidemia, peripheral lipolysis is inhibited. Reduces the extraction of free fatty acids in the liver, which leads to a decrease in the formation of TG and reduces the level of TG in blood plasma (up to 30%), due to a decrease in the level of VLDL and LPP. Reduces (up to 25%) the level of LDL, while simultaneously increasing the level of HDL, which has an anti-atherogenic effect.

Method of administration and dosage

The drug is well tolerated. Usually 600 mg is prescribed 2 times a day (morning and evening) or 900 mg 1 time (evening). The maximum daily dose is 1.5 g (patients with type V hypertriglyceridemia). The drug should be taken 30 minutes before meals without chewing, washed down with water. The course of treatment is several months, repeated courses are carried out if necessary.   Treatment of elderly patients: Application Lopid® in elderly patients is associated with a number of difficulties in dosing the drug. This is due to the presence of multiple organ changes in patients of this group, as well as the presence of concomitant therapy. In this regard, we recommend starting the use of the drug, with maximum consideration of concomitant therapy, with low initial doses.  In addition, it is necessary to take into account the greater susceptibility of elderly patients to the development of side effects. Treatment of patients with renal or hepatic insufficiency: in this category of patients, there is a higher susceptibility to the development of side effects, and therefore treatment Lopid® should be started taking into account the severity of organ changes and the presence of concomitant therapy. Patients of this category should always be treated with careful supervision by medical personnel, due to the high risk of complications.

50 reviews for Lopid

  1. Rachel Sanders –

  2. Judy Hernandez –

  3. Susan Sims –

  4. Jerry Dickerson –

  5. Sharon Parrish –

  6. Justin Bauer –

  7. Lawrence Delarosa –

  8. Jack Lyons –

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  10. Betty Trevino –

  11. Kathleen McGuire –

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  13. Rose Freeman –

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  17. Betty Zamora –

  18. Julia Harris –

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  20. Denise Horne –

  21. Elijah Francis –

  22. Sean Choi –

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  24. Philip Wilkerson –

  25. Richard Dickerson –

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  27. Carolyn Dalton –

  28. Austin Randolph –

  29. Amanda Vazquez –

  30. Sarah Thomas –

  31. Beverly Archer –

  32. Matthew Huber –

  33. Roy Travis –

  34. Alexander McCall –

  35. Logan Pugh –

  36. Terry French –

  37. Samuel Solomon –

  38. Ronald Summers –

  39. Henry Daugherty –

  40. Russell Zimmerman –

  41. Sophia Perry –

  42. Michael Gallegos –

  43. Virginia Melendez –

  44. Vincent King –

  45. Thomas Pacheco –

  46. Joan Garcia –

  47. Julie Maynard –

  48. Carol Morrow –

  49. Scott Green –

  50. Katherine Rosales –

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