(50 customer reviews)

Lopressor is a selective β1 receptor blocker prescribed in treatment of hypertension, angina, heart arrhythmia.

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hypersensitivity to metoprolol or any other component of the drug, as well as other beta-blockers; atrioventricular (AV) block of II or III degree; sinoatrial blockade; sinus bradycardia (heart rate less than 50 beats/min); sinus node weakness syndrome; cardiogenic shock; severe peripheral circulatory disorders; heart failure in the decompensation stage; age under 18 (due to lack of sufficient clinical data); simultaneous intravenous administration of verapamil; severe form of bronchial asthma; pheochromocytoma without simultaneous use of alpha-blockers. Due to insufficient clinical data, Lopressor® is contraindicated in acute myocardial infarction, accompanied by a heart rate below 45 beats/min, with a PQ interval of more than 240 ms and a sAD below 100 mm Hg. With caution: diabetes mellitus; metabolic acidosis; bronchial asthma; COPD; renal / hepatic insufficiency; myasthenia gravis; pheochromocytoma (when used simultaneously with alpha-blockers); thyrotoxicosis; AV blockade of the first degree; depression (including in anamnesis); psoriasis; obliterating peripheral vascular diseases (intermittent claudication, Raynaud’s syndrome); pregnancy; lactation; elderly; patients with a burdened allergic history (possible decrease in response with the use of adrenaline).


Symptoms: marked decrease in blood pressure, sinus bradycardia, atrioventricular block, heart failure, cardiogenic shock, asystole, nausea, vomiting, bronchospasm, cyanosis, hypoglycemia, loss of consciousness, coma. The symptoms listed above may worsen with simultaneous administration of ethanol, antihypertensive drugs, quinidine and barbiturates. The first signs of overdose appear 20 minutes – 2 hours after taking the drug. Treatment: it is necessary to carefully monitor the patient (control of blood pressure, heart rate, respiratory rate, kidney function, blood glucose concentration, serum electrolytes) in the intensive care unit. If the drug has been taken recently, gastric lavage with activated charcoal can reduce further absorption of the drug (if washing is not possible, vomiting can be caused if the patient is conscious). In case of an excessive decrease in blood pressure, bradycardia and the threat of heart failure — intravenous, beta-adrenomimetics are prescribed at intervals of 2-5 minutes – until the desired effect is achieved or 0.5–2 mg of atropine is injected. In the absence of a positive effect — dopamine, dobutamine or norepinephrine (norepinephrine). With hypoglycemia – administration of 1-10 mg of glucagon; installation of a temporary rhythm driver. With bronchospasm, beta2-adrenomimetics should be administered. With convulsions – slow intravenous administration of diazepam. Hemodialysis is ineffective.

50 reviews for Lopressor

  1. Diana Watts

  2. Louis Schmidt

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