Description
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Use in elderly patients and with liver disease
There are no special dosage instructions.
Use in patients with impaired renal function
Since pyridostigmine is excreted from the body mainly by the kidneys unchanged, in persons suffering from kidney diseases, it may be necessary to reduce the dose of the drug.
Use during pregnancy
When conducting therapy with Mestinone in pregnant women or in those who are going to become a mother, it is recommended to exercise special caution, carefully weighing the ratio of benefits and possible risks to the health of the mother and child. Pyridostigmine bromide can be used as one of the therapeutic agents in the treatment of severe myasthenia gravis in pregnant women. The average dose is 60 mg every 4 hours. During pregnancy, patients require frequent dose adjustments due to changes in absorption levels from the intestine, as well as due to changing levels of elimination through the kidneys.
Breastfeeding period
There is insufficient data on whether pyridostigmine bromide has an effect on newborns/children. Observations indicate that only a relatively small amount of pyridostigmine bromide enters the mother’s milk. If treatment is necessary, the infant should be monitored for possible exposure or breastfeeding should be discontinued.
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