(48 customer reviews)

Methotrexate is an antimetabolite used to treat certain types of cancer.

SKU: Methotrexate Category:
Where to buy Methotrexate online?


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Side effects

Central and peripheral nervous system: fatigue, dizziness, aphasia, convulsions. Hematopoiesis system: anemia, thrombocytopenia, leukopenia. Digestive system: ulcerative stomatitis, anorexia, nausea, rarely – melena, diarrhea, pancreatitis, fatty liver dystrophy. Urinary system: hematuria, cystitis. Reproductive system: oligospermia, decreased libido, menstrual disorders, impotence. Allergic reactions.


Simtoms: increased side effects. Treatment: administration of calcium folinate at a dose equal to or greater than the dose of methotrexate. Hemodialysis.


An increase in toxic effects is noted when used simultaneously with nonsteroidal anti-inflammatory drugs, barbiturates, corticosteroids, sulfonamides, tetracyclines, paraaminohippuric and paraaminobenzoic acid, probenecid, chloramphenicol. The effectiveness decreases when taking folic acid and its derivatives. Methotrexate is blocked by asparaginase with simultaneous use. Reduces the absorption of the drug with simultaneous administration of neomycin. The combination with live viral vaccines leads to an intensification of the replication of the vaccine virus and an increase in the side effects of vaccination. Enhances the effect of coumarin and indandion anticoagulants. Incompatible with nitric oxide, as the development of severe myelosuppression is possible.
Special instructions: People of reproductive age are recommended to use reliable contraceptives during treatment with methotrexate and for three months after the end of therapy.


It is used for acute lymphocytic leukemia, skin cancer, trophoblastic disease, cancer of the renal pelvis and ureters, esophageal cancer, squamous cell carcinoma of the head and neck, penile cancer, medulloblastoma, rhinoblastoma, lymphogranulomatosis. It is used for the treatment of severe forms of psoriasis and rheumatoid arthritis. 


Leukopenia, thrombocytopenia, immunodeficiency conditions, severe liver and kidney dysfunction. Individual intolerance.
With caution: Ulcers of the oral cavity and gastrointestinal tract, gout, infectious diseases, childhood and old age.

48 reviews for Methotrexate

  1. Carolyn Maldonado

  2. Judy Vincent

  3. Jerry Hughes

  4. Sarah Moyer

  5. Amy Hardin

  6. Randy Salgado

  7. Kyle Bernal

  8. Deborah Gomez

  9. Vincent Rojas

  10. Samantha Floyd

  11. Sarah Fernandez

  12. Lisa Macias

  13. Jessica Suarez

  14. Sophia Middleton

  15. Jacob Rose

  16. Sophia Faulkner

  17. Abigail Burke

  18. Samuel Flynn

  19. Peter Castaneda

  20. Ronald Atkins

  21. Jeffrey Carson

  22. Joyce Whitaker

  23. Zachary Phillips

  24. Joyce Hardin

  25. Melissa Herman

  26. Ralph Sullivan

  27. Brenda Romero

  28. Christian Taylor

  29. Doris Sheppard

  30. Brenda Schroeder

  31. Barbara Ortega

  32. Larry Terrell

  33. Donna Alfaro

  34. Joshua Paul

  35. Carolyn Payne

  36. Jacob Rich

  37. Ann Lloyd

  38. Cynthia Wheeler

  39. Shirley Jarvis

  40. Jacob Foley

  41. John Maldonado

  42. Lawrence Daniel

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  44. Stephen Bowman

  45. Christine Bennett

  46. Catherine Chung

  47. Richard Coffey

  48. Sarah Hutchinson

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