Description
Looking for a drugstore where you can order Orlistat online cheep? You can click on the button and go to the drugstore with the lowest prices. Anonymous delivery, quality medications, complete confidentiality. Go to an online drugstore and select the appropriate Orlistat dosage, and then the required amount of pills. The ordering process will be as secure and safe as possible. You can also order Orlistat with overnight delivery at the drugstore, the medicine will be delivered tomorrow. The getting is made without a prescription because we trust you and understand that you already know which medicine you need.
Pharmacokinetics
Absorption is low. Bioavailability is minimal. The bond with plasma proteins is more than 99%. Biotransformation with the formation of pharmacologically inactive metabolites – M1 (hydrolyzed four-membered lactone ring) and MZ (M1 with cleaved N-formylleucine residue) – occurs in the gastrointestinal wall. 8 hours after oral administration, the drug is not detected in plasma. Elimination with faeces – 97%, of which in unchanged form – 83%. The time of complete elimination is 3-5 days, the half-life is from 1 to 2 hours.
Indications
Obesity. Orlistat is indicated for the treatment of obesity, including reducing and maintaining body weight, in combination with a hypocaloric diet. Orlistat is also indicated to reduce the risk of repeated weight gain after its initial decrease. Orlistat is indicated for obese patients with a body mass index ≥ 30 kg / m2 or ≥ 27 kg / m2 in the presence of other risk factors (diabetes mellitus, hypertension, dyslipidemia). ICD-10
Contraindications
Hypersensitivity; – chronic malabsorption syndrome; – cholestasis; – simultaneous use with indirect anticoagulants (warfarin) or other oral anticoagulants; – simultaneous use with cyclosporine; – children under the age of 18.
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