Description

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Dosage regimen

Adults are prescribed 150 mg of roxithromycin orally at intervals of 12 hours . At the same time, the daily dose is 300 mg. It is possible to prescribe 300 mg once a day.

Children (body weight over 40 kg) 150 mg of roxithromycin is prescribed orally at intervals of 12 hours . The daily dose is 300 mg.

This dosage form is not used in children under 4 years of age!

In elderly patients, the dosage and daily dose of roxithromycin does not change.

In the presence of renal insufficiency, roxithromycin is prescribed at a dose of 150 mg 2 times / day.

In patients with hepatic insufficiency, 150 mg is prescribed once.

The duration of taking roxithromycin depends on the indication for use, the severity of the infectious process and the activity of the pathogen.

Roxithromycin is taken orally before meals 1 or 2 times / day.

The tablet should be washed down with a sufficient amount of water.

Side effect

Anaphylactic reactions: angioedema, bronchospasm, weakness, rarely anaphylactic shock.

Skin reactions: rash, redness, urticaria.

Gastrointestinal reactions: nausea, vomiting, abdominal pain, diarrhea (very rarely with blood).

Reactions from the liver: increased liver enzymes (ALT, ACT, SCHF). Cholestatic or hepatocellular acute hepatitis.

Slight changes in taste and olfactory sensations are possible.

In some cases, symptoms of pancreatitis were observed.

Dizziness, headache, paresthesia.

Superinfection may develop due to the growth of insensitive microorganisms.

Contraindications to use

simultaneous administration of drugs such as ergotamine and dihydroergotamine; hypersensitivity to macrolides.

Joint use with ergotamine derivatives and ergotamine-like vasoconstrictors is not allowed, as it can lead to the development of “ergotism” and necrosis of limb tissues.

Use with caution in patients with severe hepatic insufficiency.

Use during pregnancy and lactation

Roxithromycin is contraindicated during pregnancy. Small amounts of roxithromycin penetrate into breast milk, so it is necessary to stop breastfeeding or taking the drug.

Use in cases of impaired liver function

In patients with hepatic insufficiency, 150 mg is prescribed once.