Starlix

(35 customer reviews)

Starlix (nateglinide) is an oral diabetes medicine that helps control blood sugar levels.

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Description

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Special instructions

The risk of hypoglycemia against the background of taking nateglinide (as well as other hypoglycemic drugs) is higher in elderly patients, with reduced body weight, in the presence of adrenal or pituitary insufficiency. A decrease in the concentration of glucose in the blood can be triggered by alcohol intake, increased physical activity, as well as simultaneous administration of another hypoglycemic drug. Simultaneous use of beta-blockers can mask the manifestations of hypoglycemia. Influence on the ability to drive vehicles and manage mechanisms Patients working with mechanisms and driving vehicles should take special precautions to prevent hypoglycemia.

Pregnancy and lactation

Nateglenide did not have a teratogenic effect in experimental studies. There is currently no experience of using Starlix during pregnancy, so the safety of the drug for pregnant women has not been established. Do not use the drug during pregnancy. Nateglenide is excreted in breast milk in rats. It is not known whether Starlix is excreted in breast milk in women, therefore, due to the potential risk of hypoglycemia in breastfed infants, Starlix should not be prescribed to nursing mothers.

Method of administration and dosage

Starlix should be taken orally before meals. The time interval between taking the drug and eating should not exceed 30 minutes. As a rule, the drug is taken immediately before meals. When using Starlix as monotherapy, the recommended dose is 120 mg 3 times a day (before breakfast, lunch and dinner). If the desired effect cannot be achieved with this dosage regimen, the single dose can be increased to 180 mg. For patients whose HbA1c values are close to the target, a single dose of Starlix at the beginning of treatment may be 60 mg. Correction of the dosage regimen is carried out on the basis of regularly determined indicators of HbA1c . Combination therapy. Patients receiving Starlix monotherapy and requiring the addition of another hypoglycemic drug may additionally be prescribed metformin. On the contrary, patients already receiving metformin therapy may be prescribed Starlix at a dose of 120 mg 3 times a day (before meals) as an additional remedy. If, against the background of metformin treatment, the HbAic value approaches the desired (less than 7.5%), the Starlix dose may be less – 60 mg 3 times a day. For elderly patients, no special correction of the dosage regimen is required. For elderly patients, there were no changes in the efficacy and safety profile, as well as changes in pharmacokinetic characteristics. In patients with mild and moderate hepatic impairment, correction of the dosage regimen is not required. There were no clinically significant differences in the systemic bioavailability and T 1/2 of nateglinide in patients with mild and moderate hepatic impairment, not suffering from diabetes, compared with healthy. In patients with impaired renal function of varying severity (including those on hemodialysis), correction of the dosage regimen is not required. There were no clinically significant differences in systemic bioavailability and T 1/2 in patients with moderate and severe (creatinine clearance 15-50 ml/min/1.73 m2) impaired renal function and in patients on dialysis, compared with healthy.

35 reviews for Starlix

  1. Thomas Evans –

  2. Henry Gonzalez –

  3. Arthur Everett –

  4. Anthony Duke –

  5. Janice Glover –

  6. Elizabeth Rocha –

  7. Mark Ramirez –

  8. Grace Petersen –

  9. Debra Howell –

  10. Nicole Blevins –

  11. Carl Mathis –

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  14. Doris Lucero –

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  16. Eugene Stuart –

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  18. Kenneth Oneill –

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  20. Susan Howe –

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  25. Jesse Gonzalez –

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  27. Eric Montgomery –

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  29. Frances Hoover –

  30. Sharon Pennington –

  31. Olivia Ali –

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  33. Frances Charles –

  34. Steven Middleton –

  35. Timothy Walker –

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