Symbicort (Powder Form)

(25 customer reviews)

Symbicort is a drug in powder form for inhalation based oт budesonide and formoterol. It is an powder spray inhaled orally. Budesonide is a corticosteroid which is used to reduce inflammation. Formoterol is a slow-acting bronchodilator used for opening the bronchioles to assist respiration.

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Description

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Side effect

Against the background of the combined use of budesonide and formoterol, there was no increase in the frequency of adverse reactions. The most common adverse reactions associated with taking the drug are such pharmacologically expected adverse events for beta2-adrenomimetics as tremor and palpitations; symptoms usually have a moderate degree of severity and pass a few days after the start of treatment. During the use of budesonide in COPD, bruising and pneumonia occurred with a frequency of 10% and 6%, respectively, compared with 4% and 3% in the placebo group (p<0.001 and p<0.01, respectively). Since the drug Symbicort® Rapichaler contains two active substances, budesonide and formoterol, when it is used, undesirable effects may occur, similar in nature and intensity to the effects described for these two drugs when they are used separately. In clinical studies, diseases of the respiratory system, mainly bronchitis, nasopharyngitis, sinusitis, viral infection of the upper respiratory tract, in the group of patients receiving the drug Symbicort® 160 mcg + 4.5 mcg / dose, were observed in at least 3% of patients and more often than in the placebo group. Adverse reactions associated with the use of budesonide or formoterol are presented below using preferred terms by class of systems and organs and indicating the absolute frequency. The frequency of reactions is presented in the following gradation: very often (≥1/10), often (≥1/100, <1/10), infrequently (≥1/1000, <1/100), rarely (≥1/10000, <1/1000), very rarely (<1/10000). From the nervous system: often – headache, tremor; infrequently – dizziness; very rarely – a change in taste sensitivity. Mental disorders: infrequently – psychomotor agitation, anxiety, sleep disorders, anxiety, nervousness; very rarely – depression, behavior change (mainly in children). Infections and infestations: often – oropharyngeal candidiasis. From the immune system: hypersensitivity reactions of immediate and delayed type (for example, dermatitis, exanthema, urticaria, itching, contact eczema, angioedema and anaphylactic reaction). From the side of metabolism: very rarely – hyperglycemia, hypokalemia, signs and symptoms of systemic effects of glucocorticoids (including decreased function of the adrenal cortex). From the cardiovascular system: often – palpitations; infrequently – tachycardia; cardiac arrhythmias (for example, atrial fibrillation, supraventricular tachycardia, extrasystole); very rarely – angina pectoris, changes in blood pressure. From the respiratory system: often – cough, hoarseness of voice, slight irritation of the mucous membrane of the pharynx with swallowing disorders; rarely – bronchospasm; very rarely – paradoxical bronchospasm. From the musculoskeletal system: infrequently – muscle cramps, muscle pain. From the digestive system: infrequently – nausea. From the skin and subcutaneous tissue: rarely – bruises. It is possible to develop systemic effects of inhaled corticosteroids (adrenal insufficiency, hypercorticism, decreased growth rate in children and adolescents, cataracts, glaucoma, increased intraocular pressure in rare cases), especially with prolonged use of the drug in high doses. The use of beta2-adrenomimetics can lead to an increase in the blood content of insulin, free fatty acids, glycerol and ketone bodies.

 

25 reviews for Symbicort (Powder Form)

  1. Jean Fields

  2. Diane Oneill

  3. Nicole Weaver

  4. Sarah Fry

  5. Frances Wilcox

  6. Vincent Villa

  7. Ronald Padilla

  8. Betty Bass

  9. Lisa McCormick

  10. Sharon Kemp

  11. Marilyn Hawkins

  12. Jacob Johns

  13. Nathan Harding

  14. Sean Rose

  15. Dylan Browning

  16. Betty Rosas

  17. Christine Crane

  18. Amber Walters

  19. Aaron Chandler

  20. Nicholas Pratt

  21. Adam McDowell

  22. Joseph Payne

  23. Kelly Ferguson

  24. Evelyn Humphrey

  25. Jennifer Browning

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