Description
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Dosage Regimen
Inside, without chewing, after eating, with a sufficient amount of liquid, adults and children from 8 years old – 2-3 caps. per day. If the patient is unable to swallow the capsule, it can be opened and, without chewing, take the contents. Inside, 1 time a day, in the morning. Children with a body weight from 15 to 20 kg – 200-300 mg (no more); from 20 to 25 kg – 300-400 mg (no more); more than 25 kg – 2 tables of 200 mg (no more than 500 mg / day). Adults — 2 tablets of 350 mg (but not more than 2.5 tablets). Inside, 200-400 mg 4 times a day (a maintenance dose of 800-1200 mg per day). For children aged 10-14 years, the initial daily dose is 22 mg / kg in 4 doses, the maintenance dose is 15-22 mg / kg in 4 doses. Inside, without chewing, 30 minutes before meals – 250 mg 2 times a day (with night attacks of suffocation, the evening dose is increased 1.5-2 times and taken at 22-24 hours). Children (weighing up to 30 kg) – 10-20 mg / kg / day for 2 doses. Inside, without chewing and drinking water. 10 mg / kg / day in 2 doses, with insufficient effect and no side effects, the dose is increased by 150 mg / day; during the exacerbation of bronchial asthma – up to 600 mg 2 times a day. When using large doses (9 g per day) — on the third day, the concentration of theophylline in plasma is determined 4 hours after morning intake. For children over 3 years of age, the average dose is 10-16 mg / kg (maximum – 20 mg / kg) per day. Inside, after eating, without chewing and drinking water. Adults and children weighing more than 40 kg at the beginning of treatment are usually 350 mg 1 time a day (in the evening), the maintenance dose is 350 mg 2 times a day. Adults with reduced body weight and children weighing more than 20 kg — at the beginning of treatment 200 mg 1 time a day (in the evening), then 200 mg 2 times a day. During treatment, the dose is adjusted depending on the level of theophylline in the blood serum, which should be 10-20 mcg / ml.
Joseph Silva –
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