(23 customer reviews)

Zofran is a prescription medicine that has been licensed to prevent nausea and vomiting due to several causes

SKU: Zofran Category:
Where to buy Zofran online?


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Special instructions

In some cases, individuals with a history of hypersensitivity to other serotonin 5HT3 receptor antagonists have allergic reactions to ondansetron. Since it is known that ondansetron increases the passage time of the contents through the colon, in the case of the drug in patients with symptoms of subacute intestinal obstruction, regular monitoring is necessary. Use in pediatrics Currently, there are limited data on the use of ondansetron in children under the age of 1 month. Influence on the ability to drive vehicles and mechanisms Zofran® it does not have a sedative effect and does not affect the ability of patients to drive vehicles or engage in other potentially dangerous activities that require increased concentration of attention and speed of psychomotor reactions.


Currently, there is little data on overdose of ondansetron. Symptoms: in most of the observed cases, the symptoms of overdose coincided with adverse reactions that occur when taking Zofran® in the recommended doses. Treatment: there is no specific antidote for Zofran, therefore, if an overdose is suspected, symptomatic and supportive therapy is recommended. Drug interaction There is no evidence that ondansetron induces or inhibits the metabolism of other drugs often prescribed in combination with it. According to special studies, it was found that ondansetron does not interact with ethanol, temazepam, furosemide, tramadol and propofol. Ondansetron is metabolized by several isoenzymes of the cytochrome P450 system (CYP3A4, CYP2D6 and CYP1A2). Due to the variety of isoenzymes capable of metabolizing ondansetron, inhibition of isoenzymes or a decrease in the activity of one of the isoenzymes (for example, with a genetic deficiency of CYP2D6) is usually compensated by other isoenzymes, as a result of which changes in the total clearance of ondansetron are either absent or insignificant and practically do not require dose adjustment. Data on deep arterial hypotension and loss of consciousness during the use of ondansetron with apomorphine hydrochloride were obtained, given this, this combination is contraindicated. In patients receiving powerful inducers of CYP3A4 (phenytoin, carbamazepine and rifampicin), the concentration of ondansentron in the blood was reduced. There is evidence from small studies indicating that ondansetron may reduce the analgesic effect of tramadol.

23 reviews for Zofran

  1. Alexander Nelson

  2. Jacob Summers

  3. Abigail Collier

  4. Amy Carroll

  5. Sophia Yang

  6. Gary Glenn

  7. Megan Acevedo

  8. Maria Hurst

  9. Sean Barr

  10. Jonathan Aguirre

  11. Raymond Sosa

  12. Kelly Cantu

  13. Thomas Bender

  14. Alexander Gilmore

  15. Sophia Castaneda

  16. Anna Esquivel

  17. Jennifer Cuevas

  18. Nicholas Dorsey

  19. Elijah Galindo

  20. Aaron Douglas

  21. Linda Macias

  22. Kathryn Browning

  23. Emily Olson

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